During the period of independence, the countries of the South Caucasus passed their first new constitution in 1995 and amended these laws several times in the following years. The coincidence of these reforms with the escalation of tensions with neighbors; The domestic political atmosphere of these countries has affected the national interests of the neighbors. Considering this issue, the main question of this article is, what effect do the amendments to the constitutions of Azerbaijan and Armenia have on the national interests of the Islamic Republic of Iran? A comparative study of this issue shows the similarities and differences between these countries that may be experienced in other developing countries and neighbors. To answer the main question, the background of recent developments, especially the political atmosphere governing the main players and the legal consequences of any changes in regional approaches, as well as the international consequences of each reform, should be considered and analyzed. The main hypothesis of this article is that in South Caucasus countries, especially the Republic of Azerbaijan and Armenia, the design of a mechanism to stabilize the power of rulers, increase people's participation in governance and also prevent the influence of regional actors to interfere in the internal affairs of these countries. The analysis of the trends shows that these reforms have led to an increase in border tension between these countries and endangering Iran's national interests. The method of this research is descriptive-analytical.