In this research, we will investigate the developments of the political borders of Azerbaijan and Armenia and its impact on the national interests of the Islamic Republic of Iran with an approach to international criminal law. The research method is applied in terms of purpose and descriptive-analytical in terms of method. Considering the prohibition of resorting to force and the need for peaceful settlement of international disputes, which is explicitly recognized in the United Nations Charter as the most important goals and principles of the United Nations, the encroachment of countries on each other's territory is a serious violation of international rules and regulations. It is one of the United Nations Charter. Therefore, any country that seizes the territory of another country by resorting to force is condemned from the point of view of international criminal law. Considering the recent threats of the Republic of Azerbaijan to seize a part of Sivnik province of Armenia and cut off the land connection between Iran and Armenia, the national interests of the Islamic Republic of Iran will face serious challenges, so it is necessary for Iran to inform the international organizations and organizations about this issue. make it sensitive and prevent this from happening.